Dr. Roberto Arreguín Espinosa

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Chemistry of Biomacromolecules

Researcher
Address: Circuito Exterior s/n, Ciudad Universitaria.District Coyoacán.
ZIP Code 04510

 Mexico City. Mexico

 

Telephone: +52 (55) 56-22-44-68
Fax: +52 (55) 56-16-22-17

                                                                            

 

 

 

ACADEMIC SUMMARY

Visiting researcher at Johann Wolfgang Goethe University, Frankfurt, Germany, 1997.
Visiting researcher at the Louisiana State University, USA, 1992.
Ph.D. Biology. National Autonomous University of Mexico, 1991.
Master’s Degree. Biology. National Autonomous University of Mexico, 1986.
BSc. Biology. National Autonomous University of Mexico, 1983.

 

 

RESEARCH TOPICS

Our research is focused on the understanding of the structure and function of proteins. Within this field, marine organisms are studied with the aim to search for bioactive substances which may be used as potential drugs in the pharmaceutical industry.

We carry out studies of biomineralization occurring in marine sponges and sea stars, with the purpose of understanding the molecular bases of this process.

Within the Marine Biology topic, research on new biochemical techniques for the isolation and purification of proteins and enzymes of marine organisms is underway. Likewise, studies on the structural determination and conformational changes of proteins in solution, employing spectroscopic techniques, such as circular dichroism, nuclear magnetic resonance, differential spectroscopy in ultraviolet and high resolution mass spectrometry.

 
 

TEACHING ACTIVITIES

Lecturer at the graduate program in Marine and Limnology Sciences, UNAM, since 2000.

Lecturer at the graduate program in Biochemical Sciences, UNAM, since 2002.

Lecturer at the graduate program in the School of Sciences (Biology), UNAM, since 2003.

Supervisor on 27 graduate students’ thesis.

 

 

AWARDS AND HONORS

Grant from the International Atomic Energy Organism and German government, for a six months academic visit at the Johann Wolfgang Goethe University in Frankfurt, 1997.

Head of the Biochemistry Department, from 1999 to January 2002.

Substitute Representative at the University Council, 2002-2006.

Member of the Internal Council, Institute of Chemistry, 2003-2004.

Member of the Committee for the Evaluation of Projects submitted for funding, UNAM, 2004, 2005, 2006, 2007, 2008, 2009.

Regular Member of the Mexican Academy of Sciences, November 11, 2003.

Member of the Academic Committee of the graduate program in Marine and Limnology Sciences, since 2004.

Member of the Committee for Evaluation of Projects submitted for funding, CONACYT, 2005, 2006, 2007, 2008.


RECENT PUBLICATIONS

The inactive and active forms of the PQQ-alcohol dehydrogenase from Guconacetobacter diazotrophicus differ in the redox state of their respective prosthetic groups. Gómez-Manzo, S; González-Valdez, A; Oria-Hernández J; Reyes-Vivas, H; Arreguín-Espinosa R; Kroneck, P; Sosa-Torres M; and. Escamilla, J. E. FEMS Microbiology Letters 328 (2): 106-113, 2012. F.I. 2.04 Online ISSN: 1574-6968 Print ISSN: 0378-1097.

Controlling the morphology of silica-carbonate biomorphs using proteins involved in biomineralization. N. Sánchez-Puig, E. Guerra-Flores, F. López-Sánchez, P. A. Juárez-Espinoza, R. Ruiz-Arellano, R. González-Muñoz, R. Arreguín-Espinosa and A. Moreno. Journal of Materials Science 47 (6): 2943-2950, 2012. F.I. 1.859 Print ISSN: 0022-2461 Online ISSN: 1573-4803.

Biochemical characterization of recombinant L-asparaginase (AnsA) from Rhizobium etli, a member of an increasing Rhizobial-type family of L-asparaginase. Angélica Moreno-Enríquez, Zahaed Evangelista-Martínez, Edith G. González-Mondragón, Arturo Calderón-Flores, Roberto Arreguín, Ernesto Pérez-Rueda & Alejandro Huerta-Saquero. Journal of Microbiology and Biotechnology. 22 ( 3): 292-300, 2012. F.I. 2.06 Print ISSN: 0099-2240 Online ISSN: 1098-5336.

The role of vitamin B12 on methylmalonyl-CoA mutase activity. Tóshiko Takahashi-Iñiguez, Enrique García-Hernández, Roberto Arreguín-Espinosa, María Elena Flores. Journal of Zhejiang University SCIENCE B. Vol 13 (6): 423-437, 2012. F.I. 1.679. Print ISSN: 1673-1581 Online ISSN: 1862-1783.

Bioactive peptides from marine organisms: a short overview. Fernando Lazcano-Pérez; Sergio A. Román-González; Nuria Sánchez-Puig; Roberto Arreguín-Espinosa *. Protein and Peptide Letters. 19 (7): 700-707, 2012. F.I. 1.849. Online ISSN: 1875-5305 Print ISSN: 0929-8665.

Arrhythmogenic effect of a crude extract from sea anemone Condylactis gigantea: Possible involvement of rErg1 channels. Yúlica Santos, Martín Martínez, Alejandro Sandoval, Armando Rodríguez, Andrés Falcón, Edgar Heimer de la Cotera, Manuel Aguilar, Pedro Flores, Ricardo Félix and Roberto Arreguín-Espinosa *. Toxicon. 67: 47-54, 2013. F.I. 2.849. Print ISSN: 0041-0101 Online ISSN: 1879-3150 Link ISSN: 0041-0101.

An electrically-assisted device for protein crystallization in a vapor diffusion set-up. Edith Flores-Hernández, Vivian Stojanoff, Roberto Arreguín-Espinosa, Abel Moreno and Nuria Sánchez -Puig. Journal of Applied Crystallography. 46 (3): 832-834, 2013. F.I. 5.15 Print ISSN: 0021-8898 Online ISSN: 1600-5767 Link ISSN: 0021-8898.

A Conus regularis Conotoxin with a Novel Eight-Cysteine Framework Inhibits CaV2.2 Channels and Displays an Anti-Nociceptive Activity. Johanna Bernáldez, Sergio Román-González, Oscar Martínez, Samanta Jiménez, Oscar Vivas , Isabel Arenas, Guillermo Barraza, Gerardo Corzo, Roberto Arreguín, David E. García, Lourival D. Possani and Alexei Licea. Marine Drugs. 11: 1188-1202, 2013. F.I. 3.978 ISSN: 1660-3397 ESSN: 1660-3397.

Purification and characterization of structural and functional properties of two lectins from a marine Spheciospongia vesparia. Bertha Fenton, Roberto Arreguín, Espinosa Edgar Vázquez Contreras, Barbarin Arreguín Lozano, Norma Sánchez Sánchez, Enrique García Hernández and Edgar Zenteno Galindo. Indian Journal of Biochemistry & Biophysics 50: 562-569, 2013. F.I. 1.026 Online ISSN: 0975-0959 Print ISSN: 0301-1208.

The 2-oxoglutarate supply exerts significant control on the lysine synthesis flux in Saccharomyces cerevisiae. Quezada H, Marín-Hernández A, Arreguín-Espinosa R, Rumjanek FD, Moreno-Sánchez R and Saavedra E. FEBS Journal 280 (22): 5737-5749, 2013. F.I. 4.25 Online ISSN: 1742-4658 ISSN: 1742-464X.

Lipoprotein N-acyl tranferase (Lnt1) is dispensable for protein O-mannosylation by Streptomyces coelicolor. Córdoba-Dávalos LE, Espitia C, González-Cerón G, Arreguín-Espinosa R, Soberón-Chávez G, Servín-González L. FEMS Microbiol Lett. doi: 10.1111/1574-6968.12298, 2014. . F.I. 2.049 Online ISSN: 1574-6968 Print ISSN: 0378-10972.049 Online ISSN: 1574-6968 Print ISSN: 0378-1097.

 

Purification and biochemical characterization of a protease inhibitor II family from jalapeño pepper (Capsicum annuum L). Carrillo, J., Arreguin, R., Muñoz, J. & Soriano, M. Advances in bioscience and biotechnology: 2014 ISSN Print: 2156-8456 ISSN online: 2156-8502 En Prensa.

X-ray crystal structure of the passenger domain of plasmid encoded toxin (Pet), an autotransporter enterotoxin from enteroaggregative Escherichia coli (EAEC). Domingo Meza-Aguilar, J., Fromme, P., Torres-Larios, A., Mendoza-Hernández, G., Hernandez-Chiñas, U., Arreguin-Espinosa de los Monteros, R. A., & Eslava, C. Biochemical and biophysical research communications, 445(2), 439-444: 2014 F.I.: 2.406 ISSN: 0006-291X.

A purified Palythoa venom fraction delays sodium current inactivation in sympathetic neurons. Lazcano-Perez, Fernando, Vivas, Oscar, Roman-Gonzalez, S, Rodriguez-Bustamante, E., Castro, H,, Arenas, I., Garcia, D., Sanchez, N., & Arreguin-Espinosa de los Monteros, R. Toxicon 82, 112-116: 2014 F.I. 2.849. Print ISSN: 0041-0101 Online ISSN: 1879-3150 Link ISSN: 0041-0101.

 

 




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