• Farmacología General. CICS-IPN.
• Farmacología General. Escuela de Ciencias Químicas de la BUAP.
• Evaluación Experimental de Fármacos. Dpto. de Sistemas Biológicos de la UAM-Xochimilco.
• Biostadística Aplícada. Dpto. de Química y Biología de la Universidad de las Americas-Cholula.
• Farmacología General en la Facultad de Medicina-UNAM.
• Interacciones Fármaco-Organismo programa de maestría en Ciencias Farmacéuticas, UAM-Xochimilco.

NIVEL PRIDE: Nivel C

Reconocimiento Sor Juana Inés de la Cruz, 2015.

SNI NIVEL I Área: Biología y Química. Disciplina: Farmacología y Toxicología.

1. Rocha-Del Castillo, E.; Gómez-García, O.; Andrade-Pavón, D.; Villa-Tanaca, L.; Ramírez-Apan, T.; Nieto-Camacho, A.; Gómez, E.* Dibutyltin(IV) Complexes Derived from L-DOPA: Synthesis, Molecular Docking, Cytotoxic and Antifungal Acti- vity. Chem. Pharm. Bull. 2018, 66, 1104-1113. http://doi.org/10.1248/cpb.c18-00441

2. Alejandra Chávez-Riverosa⁎, Abigail Cruz Noriega, María Teresa Ramírez Apana, Luis D. Mirandaa, Eugene Bratoeff. Synthesis and cytotoxic effect of pregnenolone derivatives with one or two α,β-unsaturated carbonyls and an ester moiety at C-21 or C-3. Steroids 131 (2018) 37–45. 

3. Mariana Lozano-Gonzalez, ab Marıa Teresa Ramírez-Apan, Antonio Nieto-Camacho,Ruben Alfredo Toscano Ana Laura Sanchez-Sandovald and Cecilio Alvarez-ToledanoAnticarcinogenic and metal chelation properties of novel hydroxybenzylidene-1-indanone derivatives in the U-251 glioblastoma cell line. New J. Chem. 42, 387, 2018.

4. Eduardo Hernandez-Vazquez,] Alejandra Chavez-Riveros,[Adriana Romo-Perez, Maria Teresa Ramarez-Apan,[ Alma D. Chavez-Blanco, Roció Morales-Bercenas, Alfonso DueÇas-Gonzalez, and Luis D. Miranda. Cytotoxic Activity and Structure–Activity Relationship of Triazole-Containing Bis(Aryl Ether) Macrocycles. Chem Med Chem 2018, 13, 1193 – 1209.

5. Julio César Ramírez-Arroniz, Elena Martínez Klimova, Luis Daniel Pedro-Hernández, Ulises Organista-Mateos, Sandra Cortez-Maya, Teresa Ramírez-Ápan, Antonio Nieto-Camacho, José Calderón-Pardo & Marcos Martínez-García. Water-soluble porphyrin-PAMAM-conjugates of melphalan and their anticancer activity. Drug Development and Industrial Pharmacy, 2018. 44:8, 1342-1349.

6. Salma Padilla-Monroy, Elena Martínez-Klimova, Teresa Ramírez-Ápan, Antonio Nieto-Camacho, José Calderón-Pardo, Marcos Martínez-García. Porphyrin conjugates of Ibuprofen and their antiproliferative activity against human prostate and breast cancer cells. Biointerface Research in Applied Chemistry   Volume 8, Issue 1, 2018, 3039 – 3047.

7. Verónica Egas , Estrella Millán Juan A. Collado Teresa Ramírez-Apan, Carlos A. Méndez-Cuesta, Eduardo Muñoz, Guillermo Delgado. Effect of natural and semi-synthetic cadinanes from Heterotheca inuloides on NF-jB, Nrf2 and STAT3 signaling pathways and evaluation of their in vitro cytotoxicity in human cancer cell lines Bioorganic & Medicinal Chemistry 25 (2017) 3135–3147.

8. Jose M. Galvan-Hidalgo, Teresa Ramírez-Apan, Antonio Nieto-Camacho, Simon Hernandez-Ortega, Elizabeth Gomez. Schiff base Sn(IV) complexes as cytotoxic agents: Synthesis, structure, isosteric and bioisosteric replacement. Journal of Organometallic Chemistry 848 (2017) 332e343.

9. Marco A. Obregón-Mendoza, María Mirian Estévez-Carmona Simón Hernández-Ortega Manuel Soriano-García, María Teresa Ramírez-Apan, Laura Orea, Hugo Pilotzi, Dino Gnecco, Julia Cassani ,and Raúl G. Enríquez. Retro-Curcuminoids as Mimics of Dehydrozingeroneand Curcumin: Synthesis, NMR, X-ray, and Cytotoxic Activity. Molecules 2017, 22, 33.

10. Luis D. Pedro-Hernández  , Elena Martínez-Klimova, Sandra Cortez-Maya, Sonia Mendoza-Cardozo Teresa Ramírez-Ápan  and Marcos Martínez-García. Synthesis, Characterization, and Nanomedical Applications of Conjugates between Resorcinarene-Dendrimers and Ibuprofen.. Nanomaterials 2017, 7, 163.

11. Omar Gómez-García ,Elizabeth Gómez, César Monzón-González, Teresa Ramírez-Apan, and Cecilio Álvarez-Toledano. An Efficient Strategy for the Synthesis of 1-(Trifluoromethylsulfonamido)- propan-2-yl Esters and the Evaluation of Their Cytotoxic Activity. Chem. Pharm. Bull. 65, 248–252 (2017).

ANTERIORES

1. Soto-Castro D., Jorge A. Cruz-Morales , María Teresa Ramírez Apan , Patricia Guadarrama SOLUBILIZATION AND ANTICANCER-ACTIVITY ENHANCEMENT OF METHOTREXATE BY NOVEL DENDRIMERIC NANODEVICES SYNTHESIZED IN ONE-STEP REACTION. Inorganic Chemistry : 41-42, 13–21, 2012 (ISSN:0045-2068).

2. Cortez –Maya Sandra, Cortes Cortés. E., Hernández-Ortega S., Ramírez Apan-T., Nieto Camacho A., Lijanova I.V., and Martínez-García M, ANTICANCER ACTIVITY AND ANTI-INFLAMMATORY STUDIES OF 5-ARYL-1.4-BENZODIAZEPINE DERIVATIVES . Anti-Cancer Agents in Medicinal Chemistry 12 (6): 611-618, 2012. (ISSN: 1871-5206).

3. Concepción Lozada, C., Soria-Arteche O., Ramírez Apan M. T., Nieto-Camacho A., Enríquez R.G., Izquierdo T., Jiménez-Corona A. SYNTHESIS,CYTOTOXIC AND ANTIOXIDANT EVALUATIONS OF AMINO DERIVATIVES FROM PEREZONE. Bioorganic & Medicinal Chemistry 20: 5077-5084, 2012.

4.Gutiérrez-Hernández A.I., López-Cortés J.G. Ortega-Alfaro M.C., Ramírez-Apan M.T., Cázares-Marinero J.J. and Toscano R.A., FERROCENYLSELENOAMIDES: SYNTESIS, CHARACTERIZATION AND CYTOTOXIC PROPERTIES. J. Medicinal Chemistry 55:4652-4663,2012 (ISSN 1573-4064).

5.Cervini-Silva, J., Nieto-Camacho, A., Palacios, E., Montoya,J.A., Gómez-Vidales, V., Ramírez-Apán M.T. ANTI-INFLAMMATORY AND ANTI-BACTERIAL ACTIVITY, AND CYTOTOXICITY OFHALLOYSITE SURFACES. Colloids and Surfaces B: Biointerfaces 111: 651– 655, 2013 (ISSN:0927-7765).

6.Ramírez-Jiménez, A., Luna-García, R., Cortés-Lozada, A., Simón Hernández, Ramírez-Apan, T., Nieto-Camacho, A., Elizabeth GómezDINUCLEAR HEPTACOORDINATE DIBUTYLTIN (IV) COMPLEXES DERIVED FROM SCHIFF BASES AND DICARBOXYLATES: SYNTHESIS, CYTOTOXICITY, AND ANTIOXIDANT ACTIVITY. Journal of Organometallic Chemistry 738: 10-19, 2013 (ISSN:0022-328x).

7. Chans, G. M.; Nieto-Camacho, A.; Ramírez-Apan, T.; Hernández-Ortega, S.; Álvarez-Toledano, C.; Gómez, E.* Synthetic, spectroscopic, crystallographic, and biological studies of seven-coordinated Diorganotin(IV) complexes derived from Schiff bases and pyridinic carboxylic acids. Aust. J. Chem. 2016, 69, 279-290. DOI: 10.1071/CH15344 [1.427].

8. Ramírez-Rave, S.; Ramírez-Apan, M.T.; Tlahuext, H.; Morales-Morales, D.*; Toscano, R. A.; Grévy, J.-M.* Non-symmetric CNS-Pt(II) pincer complexes including thioether functionalized iminophosphoranes. Evaluation of their in vitro anticancer activity. J. Organomet. Chem. 2016, 814, 16-24 DOI: 10.1016/j.jorganchem.2016.04.022 [2.336].

9. Cervini-Silva, J.*; Nieto Camacho, A.; Palacios, E.; del Angel, P.; Pentrak, M.; Pentrakova, L.; Kaufhold, S.; Ufer, K.; Ramírez-Apan, M. T.; Gómez-Vidales, V.; Rodríguez-Montano, D.; Montoya, A.; Stucki, J. W.; Theng, B.K.G. Anti-inflammatory, antibacterial, and cytotoxic activity by natural matrices of nano-iron(hydr)oxide/halloysite. Appl. Clay Sci. 2016, 120, 101-110. DOI: 10.1016/j.clay.2015.10.004 [2.586].

10. Cervini-Silva, J.* ; Ramírez-Apan, M. T.; Kaufhold, S. ; Ufer, K. ; Palacios, E.; Montoya, A. Role of bentonite clays on cell growth. Chemosphere 2016, 149, 57-61. DOI: 10.1016/j.chemosphere.2016.01.077 [3.698].

11. Cortés-Benítez, F.; Cabeza, M.; Ramírez-Apan, M.T.; Álvarez-Manrique, B.; Bratoeff, E. Synthesis of 17β-N-arylcarbamoylandrost-4-en-3-one derivatives and their anti-proliferative effect on human androgen-sensitive LNCaP cell line. Eur. J. Med. Chem. 2016, 121, 737-746. DOI: 10.1016/j.ejmech.2016.05.059 [3.902].

12. Silva-Ortiz, A.V.; Bratoeff, E.; Ramírez-Apan, M.T.; García-Becerra, R.; Ordaz-Rosado, D.; Noyola-Martínez, N.; Castillo-Bocanegra, R.; Barrera, D.* Synthesis and biological activity of two pregnane derivatives with a triazole or imidazole ring at C-21. J. Steroid Biochem. 2016, 159, 8-18. DOI: 10.1016/j.jsbmb.2016.02.013 [3.985].

13. García-Valdés, J.; Sánchez García, J.J.; Sánchez-Castell, A.; Alpizar-Mora, A.G.; Flores-Álamo, M.; Martínez-Klimo- va, E.; Ramírez Apan, T.; Klimova, E.I.* Bis-cations with two 2,3-diferrocenylcyclopropenium fragments stabilized with diamino-alkanes: Synthesis and cytotoxic activity. J. In- org. Biochem. 2019, 197, 110689.http://doi.org/10.1016/j.jinorgbio.2019.04.003

14.Chávez-Riveros, A.; Hernández-Vázquez, E.; Nieto-Cama- cho, A.; Ramírez-Apan, T.; Miranda, L.D.* Synthesis of di-phenylamine macrocycles and their anti-inflammatory effects.Org. Biomol. Chem. 2019, 17, 1423-1435.http://doi.org/10.1039/c8ob03121e